I'm not sure suppressing IGF-1 will have the same effect. Two nearby points from the article: > This is unusual — very few if any other animals have such an ex

I'm not sure suppressing IGF-1 will have the same effect. Two nearby points from the article: > This is unusual — very few if any other animals have such an extreme lifespan variation within the same species. > Part of this lifespan disparity comes from the process of selective breeding that “created” these dog breeds. And from wiki: > A 2022 review found that both high and low levels of IGF‐1 increase mortality risk, whilst a mid‐range (120–160 ng/ml) is associated with the lowest mortality.[1] [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844108/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844108/