It's not completely clear to me (maybe I skimmed too much), but I don't think the drug is meant to be administered during the early years of the dog's life. The

It's not completely clear to me (maybe I skimmed too much), but I don't think the drug is meant to be administered during the early years of the dog's life. They let it grow to the normal size, but then begin reducing the expression of IGF-1... I think. So size should not be impacted, but lifespan is extended.