Prions are just naked proteins. They're scary because that makes them resistant against normal sterilizers like alcohol (nothing to dehydrate), heat (simple eno

Prions are just naked proteins. They're scary because that makes them resistant against normal sterilizers like alcohol (nothing to dehydrate), heat (simple enough to not denature easily I guess), radiation (no DNA to damage), etc., but since they're just naked organic molecules, just stick stuff in a strong oxidizer (bleach) for a few minutes if you have a reason to be worried about them. But also, you probably shouldn't have prions just floating around your environment in the first place.