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We've been on the brink of eradicating polio for something like 60 years. And then vaccine manufacturers across the world fuck up and cause an outbreak. This

We've been on the brink of eradicating polio for something like 60 years. And then vaccine manufacturers across the world fuck up and cause an outbreak. This is one of those cases that I have no sympathy for the hype piece, no sympathy for "the science", or the pharma companies making bank off of keeping this thing rolling. Only sympathy goes out to the people hurt by polio and human idiocy.

JumpCrisscross 3y ago
> then vaccine manufacturers across the world fuck up and cause an outbreak What?
- DoreenMichele 3y ago
  In recent decades, infection from vaccines based on the live virus, instead of the killed virus, has been a primary source of outbreaks. The usual mechanism: Someone who was never vaccinated changes the diaper of a child who has gotten the live vaccine, gets exposed, gets sick. Many years ago on Sixty Minutes, an elderly man who changed the diaper for his grandchild caught it and diagnosis and treatment was delayed because the doctor literally said something like "Decades ago, I would say this was polio. You have all the symptoms." and didn't consider that was possible because "we've eradicated it."
  - JumpCrisscross 3y ago
    How is that vaccine manufacturers fucking up? Also, this is literally what this article is about. (And we use the non-sterilising, non-virus containing non-polio-producing IPV in the United States. So the unvaccinated can change babies’ diapers without fear.)
    - DoreenMichele 3y ago
      I'm not suggesting it is. But "What?" is hardly a rebuttal a la "That's not a fuck up." So I explained what I think the OP likely is referring to because you sounded to me like you had no idea what they meant.
    - Izkata 3y ago
      > (And we use the non-sterilising, non-virus containing non-polio-producing IPV in the United States. So the unvaccinated can change babies’ diapers without fear.) Not necessarily. All those migrants coming into the country? Mostly they got the cheaper OPV vaccine, if they got any. There was a case of it last year in New York: https://www.cdc.gov/vaccines/vpd/polio/hcp/vaccine-derived-poliovirus-faq.html https://www.cdc.gov/vaccines/vpd/polio/hcp/vaccine-derived-p...
- flatline 3y ago
  https://www.theatlantic.com/health/archive/2022/09/polio-eradication-vaccine-loophole/671451/ https://www.theatlantic.com/health/archive/2022/09/polio-era...
- chihuahua 3y ago
  I'm not sure what exactly GP is referencing, but maybe it's the rare cases when the weakened virus in OPV mutates and someone excretes infectious, vaccine-derived poliovirus. I still don't see how that's the fault of the vaccine providers, since it's due to mutation and not a mistake in production of the vaccine, and OPV is a reasonable thing to use and certainly better than doing nothing.

JumpCrisscross 3y ago

> then vaccine manufacturers across the world fuck up and cause an outbreak What?

DoreenMichele 3y ago
In recent decades, infection from vaccines based on the live virus, instead of the killed virus, has been a primary source of outbreaks. The usual mechanism: Someone who was never vaccinated changes the diaper of a child who has gotten the live vaccine, gets exposed, gets sick. Many years ago on Sixty Minutes, an elderly man who changed the diaper for his grandchild caught it and diagnosis and treatment was delayed because the doctor literally said something like "Decades ago, I would say this was polio. You have all the symptoms." and didn't consider that was possible because "we've eradicated it."
- JumpCrisscross 3y ago
  How is that vaccine manufacturers fucking up? Also, this is literally what this article is about. (And we use the non-sterilising, non-virus containing non-polio-producing IPV in the United States. So the unvaccinated can change babies’ diapers without fear.)
  - DoreenMichele 3y ago
    I'm not suggesting it is. But "What?" is hardly a rebuttal a la "That's not a fuck up." So I explained what I think the OP likely is referring to because you sounded to me like you had no idea what they meant.
  - Izkata 3y ago
    > (And we use the non-sterilising, non-virus containing non-polio-producing IPV in the United States. So the unvaccinated can change babies’ diapers without fear.) Not necessarily. All those migrants coming into the country? Mostly they got the cheaper OPV vaccine, if they got any. There was a case of it last year in New York: https://www.cdc.gov/vaccines/vpd/polio/hcp/vaccine-derived-poliovirus-faq.html https://www.cdc.gov/vaccines/vpd/polio/hcp/vaccine-derived-p...
flatline 3y ago
https://www.theatlantic.com/health/archive/2022/09/polio-eradication-vaccine-loophole/671451/ https://www.theatlantic.com/health/archive/2022/09/polio-era...
chihuahua 3y ago
I'm not sure what exactly GP is referencing, but maybe it's the rare cases when the weakened virus in OPV mutates and someone excretes infectious, vaccine-derived poliovirus. I still don't see how that's the fault of the vaccine providers, since it's due to mutation and not a mistake in production of the vaccine, and OPV is a reasonable thing to use and certainly better than doing nothing.