This is a dated article but it does give a good overview of how the screen readers work, some items have been improved in the screen readers since 08 but for th

This is a dated article but it does give a good overview of how the screen readers work, some items have been improved in the screen readers since 08 but for the most part it is a good starting point http://northtemple.com/2008/10/07/javascript-and-screen-readers http://northtemple.com/2008/10/07/javascript-and-screen-read... also this is a good stack overflow conversation on getting the readers to read dynamic content http://stackoverflow.com/questions/3670570/getting-screen-reader-to-read-new-content-added-with-javascript http://stackoverflow.com/questions/3670570/getting-screen-re... and finally a little more bland but still containing a lot of good info the wai-aria specification http://www.w3.org/TR/wai-aria/ http://www.w3.org/TR/wai-aria/ . Also look at Dojo in my opinion they have the most advanced accessibility library out of all of the toolkits.