Content negotiation is "friendlier to humans" in the sense that you can serve the right content to different clients using the same URL, transparent to the user

Content negotiation is "friendlier to humans" in the sense that you can serve the right content to different clients using the same URL, transparent to the user. If the URL itself is never meant to be shared by the user, then I don't see the point. Say, an RSS feed being served as a formatted and styled page to a browser, or a client that accepts the usual XML.