The solar system has a north pole and a south pole based on the rotation of the Sun. Basically the only places in which there isn't something to orient against

The solar system has a north pole and a south pole based on the rotation of the Sun. Basically the only places in which there isn't something to orient against are in the depths of inter-galactic-cluster voids with nothing around. And if a being is stuck in one of those voids, orientation is way down the list of problems they have.