3 ms·

> I feel like vitamin D is utterly alien and mysterious. It is as if everyone knows it is there but nobody understands it very well. B12 is another one — B12 d

by notamy 3y ago

> I feel like vitamin D is utterly alien and mysterious. It is as if everyone knows it is there but nobody understands it very well. B12 is another one — B12 deficiency is absolutely horrific to end up with long-term, and doctors struggle to treat it properly due to extensive misconceptions[0] (ex insisting it’s impossible to have issues with oral absorption / that injections aren’t necessary). It also often gets misdiagnosed as things like MS due to them presenting very similarly in terms of symptoms[1]. [0] https://www.mcpiqojournal.org/article/S2542-4548(19)30033-5/fulltext https://www.mcpiqojournal.org/article/S2542-4548(19)30033-5/... [1] Table 1, page 12 https://researchonline.nd.edu.au/cgi/viewcontent.cgi?article=1215&context=health_article https://researchonline.nd.edu.au/cgi/viewcontent.cgi?article...

dirtyhippiefree 3y ago
That’s what stopped me doing nitrous oxide…b12.. Rave culture will be hit hard in coming years. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366039/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366039/
- esaym 3y ago
  Steve-o begs to differ.
  - dirtyhippiefree 3y ago
    …always a reliable source for role model tips… /s
- yieldcrv 3y ago
  Like 5 out of 1000 people at raves do nitrous oxide where I’m at
- zoklet-enjoyer 3y ago
  I always made sure to take B12 when using nitrous
  - dirtyhippiefree 3y ago
    If B12 uptake is restricted biologically, it may well not be enough. Besides, getting B vitamins from sources other than food is associated with cancer.
- travisjungroth 3y ago
  That case study doesn’t include how much she was using, and in every case study of a hospital visit I’ve seen that included usage habits, it was extreme. Like daily usage for months.
  - Projectiboga 3y ago
    Alcohol, Narcotics and a Vegan diet can all lower B12 levels so any of those together can cause a serious depletion.
  - dirtyhippiefree 3y ago
    Your assumption that I didn’t “sow my wild oats” is your first error. Hopefully the sibling comments here will show why I might have reason to be concerned. Eating a lot of nuts these days….
    - travisjungroth 3y ago
      Honestly, could you point out where I assumed that? I don’t think I expressed that assumption. I certainly don’t hold it. If you’re concerned about your own B12 levels, oral supplements are cheap and quite bioavailable. I do injections every 2 months since I find it more convenient than sublinguals daily. Every year I do blood tests and B12 is top of range. Not that this takes care of everything for someone still using. If I remember right, N2O blocks the processes B12 are involved in. It doesn’t just deplete it.
  - hunter2_ 3y ago
    It does, however, say: > the clinical manifestations of vitamin B12 deficiency have been noted not only in long-term nitrous oxide users, but also after a single exposure in those with susceptibility to vitamin B12 deficiency Basically, there are several sources of susceptibility, N2O being one of them, and they add up.

by notamy 3y ago

dirtyhippiefree 3y ago

That’s what stopped me doing nitrous oxide…b12.. Rave culture will be hit hard in coming years. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366039/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366039/

esaym 3y ago
Steve-o begs to differ.
- dirtyhippiefree 3y ago
  …always a reliable source for role model tips… /s
yieldcrv 3y ago
Like 5 out of 1000 people at raves do nitrous oxide where I’m at
zoklet-enjoyer 3y ago
I always made sure to take B12 when using nitrous
- dirtyhippiefree 3y ago
  If B12 uptake is restricted biologically, it may well not be enough. Besides, getting B vitamins from sources other than food is associated with cancer.
travisjungroth 3y ago
That case study doesn’t include how much she was using, and in every case study of a hospital visit I’ve seen that included usage habits, it was extreme. Like daily usage for months.
- Projectiboga 3y ago
  Alcohol, Narcotics and a Vegan diet can all lower B12 levels so any of those together can cause a serious depletion.
- dirtyhippiefree 3y ago
  Your assumption that I didn’t “sow my wild oats” is your first error. Hopefully the sibling comments here will show why I might have reason to be concerned. Eating a lot of nuts these days….
  - travisjungroth 3y ago
    Honestly, could you point out where I assumed that? I don’t think I expressed that assumption. I certainly don’t hold it. If you’re concerned about your own B12 levels, oral supplements are cheap and quite bioavailable. I do injections every 2 months since I find it more convenient than sublinguals daily. Every year I do blood tests and B12 is top of range. Not that this takes care of everything for someone still using. If I remember right, N2O blocks the processes B12 are involved in. It doesn’t just deplete it.
- hunter2_ 3y ago
  It does, however, say: > the clinical manifestations of vitamin B12 deficiency have been noted not only in long-term nitrous oxide users, but also after a single exposure in those with susceptibility to vitamin B12 deficiency Basically, there are several sources of susceptibility, N2O being one of them, and they add up.