Feldman was on Peter Attia's podcast [0] and I was not impressed. LDL seems causal in the process of ASCVD. [1] I can't think of a stronger statement in science

Feldman was on Peter Attia's podcast [0] and I was not impressed. LDL seems causal in the process of ASCVD. [1] I can't think of a stronger statement in science than one invoking causality. (In particular, it seems necessary, but not sufficient. Interestingly, it seems you can't go too low with LDL [2].) I wonder if OP could continue keto, but go on a statin/pcsk9 inhibitor/bempedoic acid/ezetimibe. Of course, these are prescriptions, so he'll need to find a willing doctor. And have money to shell out. It sucks that he's APOE4/4, since that makes him so much more susceptible to other types of metabolic/cardiovascular disease [3] 0: https://peterattiamd.com/davefeldman/ https://peterattiamd.com/davefeldman/ 1: https://pubmed.ncbi.nlm.nih.gov/28444290/ https://pubmed.ncbi.nlm.nih.gov/28444290/ 2: https://www.health.harvard.edu/blog/ldl-cholesterol-how-low-can-you-safely-go-2020012018638 https://www.health.harvard.edu/blog/ldl-cholesterol-how-low-... 3: https://peterattiamd.com/johnkastelein/ https://peterattiamd.com/johnkastelein/