3 ms·
[not what the article is about, but related topic] I first heard of dichloroacetic acid about 15 years ago - a cheap drug that also killed cancer cells by allo
by Izkata 3y ago
[not what the article is about, but related topic]
I first heard of dichloroacetic acid about 15 years ago - a cheap drug that also killed cancer cells by allowing mitochondria to induce apoptosis in the cancer cells and not in healthy cells.
https://en.wikipedia.org/wiki/Dichloroacetic_acid#Cancer https://en.wikipedia.org/wiki/Dichloroacetic_acid#Cancer
It doesn't appear to have gotten a lot of research into what would be a safe dosage, seemingly because it's an old drug that can no longer be patented.
- darkerside 3y agoInfuriating. Can we not get public research universities to fund this research???
- qup 3y agoor even to just research what are non lethal doses, and set it free
- heavyset_go 3y agoFormulations, therapies, techniques, etc can be patented even if an active ingredient can't be patented. Similarly, modification to structures, prodrugs, etc can be patented, too.
- vore 3y agohttps://cancerquest.org/patients/integrative-oncology/dichloroacetate-dca https://cancerquest.org/patients/integrative-oncology/dichlo... However, in some systems DCA has been shown to PROTECT cancer cells from death. In research with colon cancer cells, DCA prevented the death of the cells in the laboratory and in animals.28 In mice with neuroblastoma, DCA enhanced the growth of tumor cells.29 Another study showed mixed results: DCA did not slow down tumor growth in mice, though it did make it harder for cancerous cells to spread (metastasize).30