3 ms·
Next statement is > But they did find that, among those infected, those with higher "serointensity" or a higher concentration of antibodies to the parasite, we
by kelipso 3y ago
Next statement is
> But they did find that, among those infected, those with higher "serointensity" or a higher concentration of antibodies to the parasite, were significantly more likely to be frail.
which should be read as
> But they did find that, among those infected, those with higher "serointensity" (i.e., a higher concentration of antibodies to the parasite), were significantly more likely to be frail.
When they say serointensity, they specifically mean "Toxoplasma gondii IgG Serointensity" [1].
Serointensity is how strongly your immune system responds to the infection. Which is different from whether you get the infection or not (their original hypothesis).
Also, statement after the above quote is '"This paper is important because it provides, for the first time, evidence of the existence of a link between frailty in older adults and intensity of the response to T. gondii infection," said co-author Blanca Laffon [...]'.
[1] https://academic.oup.com/biomedgerontology/advance-article/doi/10.1093/gerona/glad228/7334598?login=false https://academic.oup.com/biomedgerontology/advance-article/d...
- soulofmischief 3y agoI know what serointensity is. > When they say serointensity, they specifically mean "Toxoplasma gondii IgG Serointensity" Yes, because that's what they studied. :) That doesn't mean we can draw such sharp conclusions. Next steps include compiling enough data for a meta-analysis on the variance in correlation between frailty and the serointensity of different pathogens.