4 ms·
They say there are MAOIs in tobacco that increase nicotine uptake, but I'm not entirely convinced that that's the sole culprit either. I could chew some tobacco
by friend_and_foe 3y ago
They say there are MAOIs in tobacco that increase nicotine uptake, but I'm not entirely convinced that that's the sole culprit either. I could chew some tobacco right now, or smoke a pipe or cigar, I could even inhale it, and I wouldn't have a problem. If I were to smoke a single cigarette I'd be smoking a pack a day within a week and who knows how many months or years it would take me to rectify that. Whatever it is I suspect it's done deliberately in processing.
- kallistisoft 3y agoTobacco contains Harmaline which is an MAOI - it both increases the bioavailability of nicotine as well as adding an additional psychoactive effect; stimulant + anti-depressant I've recently started adding free base harmaline to my vape juice to create a proper tobacco substitute... I found that nicotine alone didn't provide the relaxation that I would get from smoking tobacco. After a fair amount of research I discovered that it was that lack of harmala compounds. https://en.wikipedia.org/wiki/Harmala_alkaloid https://en.wikipedia.org/wiki/Harmala_alkaloid
- friend_and_foe 3y agoWell, I'm past that addiction now so I don't want to try it to stir it up, but I've had pipe tobacco and cigar tobacco, as well as chewing tobacco since I quit cigarettes and I've never had them rope me back in even a little bit. So I think cigarettes have something else going on. Maybe I'm wrong. I am curious though if this worked for you as a full substitute to sate cravings, and what amount you added.