4 ms·
Nicotine not addictive? That’s a bold claim.
by Our_Benefactors 3y ago
Nicotine not addictive? That’s a bold claim.
- goodluckchuck 3y agoThe article cites some fairly convincing studies that the addictiveness is from tobacco’s other (non-nicotine) chemicals including MAOIs. Is smoking addictive? Absolutely, but not because it contains nicotine.
- bumby 3y agoThe articles seems much more inconclusive than your comment implies. On one hand, yes, they point out that MAOIs may be confounding. But they also say: “additional work since 2002 has clearly shown that nicotine alone does have some addictive properties” And, frustratingly, they point out that addiction effects can’t be parsed out using smokers because of the confounding effects of other chemicals present in tobacco yet they quote a study using smokers to support the non-addiction claim.
- Findecanor 3y agoIf nicotine wasn't addictive then kids who never used tobacco wouldn't get hooked on vape, which they do.
- financltravsty 3y agoΔFosB expression is lower from nicotine than it is caffeine.
- mort96 3y agoI'm not familiar with the biochemistry involved or what exactly "ΔFosB expression" means, and I don't know if the term "addiction" is used in its strictly technical definition here (i.e activating the reward circuit) or if it's used to generally mean some form of dependence... but it's worth noting that caffeine dependence is pretty common.