4 ms·

IIRC peripheral neurons can heal, as in, if you cut off a finger and you sew it back on, you can regain feeling in the finger. But CNS neurons have very limited

by est31 3y ago

IIRC peripheral neurons can heal, as in, if you cut off a finger and you sew it back on, you can regain feeling in the finger. But CNS neurons have very limited healing ability, which is why spinal cord injuries are so difficult to treat. The optic nerve is considered part of the CNS.

grishka 3y ago
Tissue and organ regeneration can't really be discussed without mentioning Michael Levin and his morphogenesis research: https://www.youtube.com/watch?v=VVHhm1pwXjI https://www.youtube.com/watch?v=VVHhm1pwXjI
consumer451 3y ago
I had crazy optical nerve issues from advanced neurological Lyme earlier this year. It was like an old VGA cable wasn’t plugged in correctly and the colors didn’t quite line up. Also had a white area appearing in the center of both eyes. It was scary as heck. I was told not to expect full recovery due to what you stated. I am happy to report that taking my meds + time and I am back to 100%, as far as the vision at least. The human body is very strange.
- jmprspret 3y ago
  > The human body is very strange. And clearly sometimes quite resilient! Congrats on the recovery
- 0x7cfe 3y ago
  First of all, congrats on your recovery! The worst condition I've ever experienced myself was a massive scintillating scotoma, so I kinda can imagine how you felt. Still, as a neuroscience researcher I am very interested, if possible, in hearing a little bit more details. You mentioned a color shift. Since you compared that with a broken VGA, I assume the colors were attached to actual objects but were incorrect, right? As if someone had played with color filters in Photoshop. Did you experience color that was "detached" from an object, like a poorly calibrated printing press that shifts one of the colors a bit? What about the fills? Was it like a random color noise texture or a solid fill but with incorrect color?
ralferoo 3y ago
It doesn't need to be perfect or even "good", anything would be useful. Even if he had a dozen or so random nerves form connections and supply signals to be brain, that'd still be massively useful compared to nothing, and the brain should be able to figure out how to use that to reconstruct limited depth perception that wouldn't be possible with just one eye. I've heard of crazy experiments done in the past, e.g. one where a blind subject was given effectively a braille device on their tongue fed from a camera, so effectively a very low resolution (it might have been 8x8), and the brain was able to start correlating the pressure signals from the tongue with "sight" and the recipient learned how to avoid obstacles using their new tongue sensor. I just googled it and came up with these links: https://www.scientificamerican.com/article/device-lets-blind-see-with-tongues/ https://www.scientificamerican.com/article/device-lets-blind... https://en.wikipedia.org/wiki/Brainport https://en.wikipedia.org/wiki/Brainport

by est31 3y ago

grishka 3y ago

Tissue and organ regeneration can't really be discussed without mentioning Michael Levin and his morphogenesis research: https://www.youtube.com/watch?v=VVHhm1pwXjI https://www.youtube.com/watch?v=VVHhm1pwXjI

consumer451 3y ago

I had crazy optical nerve issues from advanced neurological Lyme earlier this year. It was like an old VGA cable wasn’t plugged in correctly and the colors didn’t quite line up. Also had a white area appearing in the center of both eyes. It was scary as heck. I was told not to expect full recovery due to what you stated. I am happy to report that taking my meds + time and I am back to 100%, as far as the vision at least. The human body is very strange.

jmprspret 3y ago
> The human body is very strange. And clearly sometimes quite resilient! Congrats on the recovery
0x7cfe 3y ago
First of all, congrats on your recovery! The worst condition I've ever experienced myself was a massive scintillating scotoma, so I kinda can imagine how you felt. Still, as a neuroscience researcher I am very interested, if possible, in hearing a little bit more details. You mentioned a color shift. Since you compared that with a broken VGA, I assume the colors were attached to actual objects but were incorrect, right? As if someone had played with color filters in Photoshop. Did you experience color that was "detached" from an object, like a poorly calibrated printing press that shifts one of the colors a bit? What about the fills? Was it like a random color noise texture or a solid fill but with incorrect color?

ralferoo 3y ago

It doesn't need to be perfect or even "good", anything would be useful. Even if he had a dozen or so random nerves form connections and supply signals to be brain, that'd still be massively useful compared to nothing, and the brain should be able to figure out how to use that to reconstruct limited depth perception that wouldn't be possible with just one eye. I've heard of crazy experiments done in the past, e.g. one where a blind subject was given effectively a braille device on their tongue fed from a camera, so effectively a very low resolution (it might have been 8x8), and the brain was able to start correlating the pressure signals from the tongue with "sight" and the recipient learned how to avoid obstacles using their new tongue sensor. I just googled it and came up with these links: https://www.scientificamerican.com/article/device-lets-blind-see-with-tongues/ https://www.scientificamerican.com/article/device-lets-blind... https://en.wikipedia.org/wiki/Brainport https://en.wikipedia.org/wiki/Brainport