Perhaps a small use case, but nasm is used in UMD's compilers course (https://www.cs.umd.edu/class/fall2023/cmsc430/ https://www.cs.umd.edu/class/fall2023/cmsc4

Perhaps a small use case, but nasm is used in UMD's compilers course (https://www.cs.umd.edu/class/fall2023/cmsc430/ https://www.cs.umd.edu/class/fall2023/cmsc430/). And while that in itself is maybe not particularly exciting, I think the underlying point is more that assemblers like nasm allow for the implementation of toolchains like this, where you have some assembly with some C code. While not common, I'm sure cases like this are also not exceedingly rare.