> Available data from a clinical lactation study in 14 women indicate that zuranolone is present in low levels in human milk (see Data). There are no data on th

> Available data from a clinical lactation study in 14 women indicate that zuranolone is present in low levels in human milk (see Data). There are no data on the effects of zuranolone on a breastfed infant and limited data on the effects on milk production. That's an immediate reject. Everyone is able to decide on how much risk their willing to take on, but I don't think it's controversial to conclude that it's ill-advised to administer a medication to infants without testing. On the other hand PPD is associated with maternal suicide, HR 19.300 (95% confidence interval (CI): 5.977–62.255)[1]. While it's not possible to conclude that Zuranolone reducing PPD would also reduce maternal suicide, avoiding that HR is notable. How much would you pay to reduce avoid feeling so bad you successfully committed suicide? 1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099720/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099720/