I'm not sure that you can make that argument fairly. Shift, on-call, across-time-zones (etc) workers have a job with a recognized hazard which is fully known at

I'm not sure that you can make that argument fairly. Shift, on-call, across-time-zones (etc) workers have a job with a recognized hazard which is fully known at the time of acceptance. If your wife did not want to deal with such a schedule then another career should have been chosen, and if she is suffering health effects now then there should be options for disability leave or transfer to a different set of responsibilities. If this is not available I would advocate for it -- but her suffering is not a reason to shift the time scale of the rest of society against their will and to their detriment. Let's do less harm to fewer people and not use some people being harmed to justify doing it to more of them.