4 ms·
I just want to emphasize that, currently, CAR-T therapies are not particularly effective for solid tumors, which make up the majority of cancer diagnoses. They'
by snitty 3y ago
I just want to emphasize that, currently, CAR-T therapies are not particularly effective for solid tumors, which make up the majority of cancer diagnoses. They're currently only good for leukemias and lymphomas. They're also not the first line of treatment, because they have to be genetically engineered from your own cells, and then reinjected into you.
There's been some progress in CAR-NK therapies, which would be "off the shelf" in that they don't need to be engineered from your own cells. Also some very preliminary work with allogeneic CAR-T therapies that wouldn't have to be made special for each person.
- konschubert 3y agoIs there any reason why the price for personalised CAR-T therapies couldn't come down dramatically? Just like the price of genome sequencing has come down?
- speleding 3y agoI'm curious as well. The article mentions $300,000 for a treatment. Can anybody give a rough breakdown of where that money goes? How much is labour / ingredients / profit?