3 ms·

Is your normal state depressed though? I don’t think it works for “normal” people.

by baxtr 3y ago

Kbelicius 3y ago
The study was done on mice. Are there depressed mouse that are used in such experiments or is this just an opinion on why zdragnar might not feel these effects? This is a genuine question.
- baxtr 3y ago
  Ah god to know. I missed the mice part… I feel the same as OP. Whenever I miss a night I’m in a terrible mood. It was just my opinion.
- WJW 3y ago
  It is possible to artificially induce depression in mice, yes. Obviously, the whole field is insanely fraught with ethical dilemmas.
zdragnar 3y ago
I was diagnosed with dysthymic depression a little over 20 years ago. Therapy helped reset my expectations for myself, meds keep me regular. I had a stint of a few years off of medication to see how it went, thinking that I was sufficiently practiced at introspection to know if I needed to start again. I was very wrong, and put it off far too long. I've been back on medication for about 7 years and don't plan on stopping, ever.
- sneed_chucker 3y ago
  What meds worked for your dysthymia?
  - zdragnar 3y ago
    The standard first-pass type SSRIs (i.e. fluoxetine) just gave me side effects, ranging from bad to very bad. Wellbutrin and effexor both worked alright, but I felt like I needed to keep ramping the dose. It is also possible that I was poorly managing my stress in high school and college. Ultimately I topped out at the highest dose, and ended up getting anxiety issues (never medicated) on top. I don't recall what I switched to after, but that was the point I tapered off of meds entirely for a few years. I ended up back on Lexapro and it has been a life saver. I also started up therapy with the Lexapro, which I realize in retrospect I should have been doing to much sooner. After a few months my therapist said I didn't need regular sessions any more, and I haven't been back since. That said, I'm aware enough to know it is a bit of a balancing act. Managing my stress levels is the biggest thing, and if something significant and negative in my life were to happen, I'd probably start up again.

Is your normal state depressed though? I don’t think it works for “normal” people.

by baxtr 3y ago

Is your normal state depressed though? I don’t think it works for “normal” people.

The study was done on mice. Are there depressed mouse that are used in such experiments or is this just an opinion on why zdragnar might not feel these effects? This is a genuine question.

baxtr 3y ago
Ah god to know. I missed the mice part… I feel the same as OP. Whenever I miss a night I’m in a terrible mood. It was just my opinion.
WJW 3y ago
It is possible to artificially induce depression in mice, yes. Obviously, the whole field is insanely fraught with ethical dilemmas.

zdragnar 3y ago

I was diagnosed with dysthymic depression a little over 20 years ago. Therapy helped reset my expectations for myself, meds keep me regular. I had a stint of a few years off of medication to see how it went, thinking that I was sufficiently practiced at introspection to know if I needed to start again. I was very wrong, and put it off far too long. I've been back on medication for about 7 years and don't plan on stopping, ever.

sneed_chucker 3y ago
What meds worked for your dysthymia?
- zdragnar 3y ago
  The standard first-pass type SSRIs (i.e. fluoxetine) just gave me side effects, ranging from bad to very bad. Wellbutrin and effexor both worked alright, but I felt like I needed to keep ramping the dose. It is also possible that I was poorly managing my stress in high school and college. Ultimately I topped out at the highest dose, and ended up getting anxiety issues (never medicated) on top. I don't recall what I switched to after, but that was the point I tapered off of meds entirely for a few years. I ended up back on Lexapro and it has been a life saver. I also started up therapy with the Lexapro, which I realize in retrospect I should have been doing to much sooner. After a few months my therapist said I didn't need regular sessions any more, and I haven't been back since. That said, I'm aware enough to know it is a bit of a balancing act. Managing my stress levels is the biggest thing, and if something significant and negative in my life were to happen, I'd probably start up again.