4 ms·
Also, and totally minor: there are nowhere close to 19k different approved small molecules. The same drug can be included in multiple products or formulations b
by pama 3y ago
Also, and totally minor: there are nowhere close to 19k different approved small molecules. The same drug can be included in multiple products or formulations bringing that number you mentioned to 19k marketed products. Each generic formulation of iboprofen increases the latter count by 1. Counting all the marketed products of pure orange juice may add up to a large number but it is still one ingredient.
- riku_iki 3y agoYes, I compare drugs with drugs, not molecules with drugs.
- pama 3y agoNo. The analysis in the paper above referred to molecules vs the snippet in the fda referred to products. More generally, other than marketing materials to doctors or patients or very rare exceptions talking about formulations etc, the scientific literature refers to the molecular entity as a drug not the particular named/branded product. I hope that the tool you are building will not mix up such concepts.
- riku_iki 3y agoThe link you posted found "1,578 US FDA-approved drugs"(exact citation).
- pama 3y agoYes that is the standard language in the field. It does not refer to the number of marketed products. Look up the number of novel drugs approved by the FDA per year. It only recently exceeded 40 per year, and the FDA has not existed for very long.
- riku_iki 3y agoif we consider that you are not making things up(which I am very not confident), then your link is useless in this discussion, because it doesn't give a sense how many non-protein targeting drugs were approved by FDA.