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This really only applies to northern Europeans. We are the only cold adapted peoples because of the ice age. But it’s a really really huge finding for more nat

This really only applies to northern Europeans. We are the only cold adapted peoples because of the ice age. But it’s a really really huge finding for more natural cures to both mood disorders and immune disorders. If zinc deficiency was tested more regularly in the population, with schizophrenia and bipolar disorder, we would probably find a lot of people would be helped by taking zinc and possibly some other supplements.

HPsquared 3y ago
Aren't quite a few people going to be cold-adapted? Inuits and native Siberians, probably many others.
- Podgajski 3y ago
  Yes, we all came in the same people. But there will be many people who inhabit Europe now who came from southern Europe and the caucuses. These people came from a later migration from Africa then the cold adapted people who came earlier. There were two migrations out of Africa, and this will determine if a person has called adapted or not.
rzmmm 3y ago
Are you sure it only applies to northern Europeans? The linked article states the genetic variant is found all over the planet, although it's less frequent in Africa.
jyscao 3y ago
>This really only applies to northern Europeans. We are the only cold adapted peoples because of the ice age. Incorrect. Northeast Asians had to deal with arguably harsher cold climates than northern Europeans. Some examples of research on this subject (just the first couple I found through search): * Extreme climate, rather than population history, explains mid-facial morphology of Northern Asians (https://pubmed.ncbi.nlm.nih.gov/24374801/ https://pubmed.ncbi.nlm.nih.gov/24374801/) * Searching for Signatures of Cold Climate Adaptation in TRPM8 Gene in Populations of East Asian Ancestry (https://www.frontiersin.org/articles/10.3389/fgene.2019.00759/full https://www.frontiersin.org/articles/10.3389/fgene.2019.0075...) Not to mention, this article on the zinc metabolism gene variant explicitly states: >Although the variant was established in Asia as a result of interbreeding between Denisovans and sapiens, it also spread to European and native American populations.
- Podgajski 3y ago
  Those east Asians are carrying the same cold adapted genes from the same people the Northern Europeans got them from. The Denisovans and Neanderthal have a common ancestor. https://evolution.berkeley.edu/wp-content/uploads/2020/08/evo-news-denisovans.jpg https://evolution.berkeley.edu/wp-content/uploads/2020/08/ev... The ice age you’re talking about and what I’m talking about are different. The age I’m talking about is the one that caused that split. And it happened 400,000 years ago. https://cdn.serc.carleton.edu/images/eslabs/cryosphere/timeline_ice_ages_456.webp https://cdn.serc.carleton.edu/images/eslabs/cryosphere/timel... These are extremely ancient cold adaptive genes. From the study: “ Given the essential role of the mitochondria in skeletal muscle thermogenesis, we propose that the derived G allele, which we have shown provides better protection to the mitochondria, may have been positively selected to facilitate adaptation to cold while providing higher susceptibility to neuropsychiatric traits. This is a plausible scenario for a case of archaic adaptive introgression, as Denisovans and Neanderthals were probably already well adapted to the local environmental conditions modern humans encountered when expanding across Eurasia.” I admit to my over generalization Only because it can get too complicated explaining it all on HN.
bitxbitxbitcoin 3y ago
The Western centric view of world history strikes again. The article is talking about Denisovans and last I checked, Denisova Cave wasn’t in Northern Europe.
- Podgajski 3y ago
  Yeah, I’m sorry I was over generalizing and I was being Eurocentric for a reason. But the Denisovans and the Neanderthals both came from the same ancestor during the Ice Age I’m talking about which was 400,000 years ago. These people were split because of the ice age. And that’s what caused the same cold adapted genes. From the study: Given the essential role of the mitochondria in skeletal muscle thermogenesis, we propose that the derived G allele, which we have shown provides better protection to the mitochondria, may have been positively selected to facilitate adaptation to cold while providing higher susceptibility to neuropsychiatric traits. This is a plausible scenario for a case of archaic adaptive introgression, as Denisovans and Neanderthals were probably already well adapted to the local environmental conditions modern humans encountered when expanding across Eurasia.

HPsquared 3y ago

Aren't quite a few people going to be cold-adapted? Inuits and native Siberians, probably many others.

Podgajski 3y ago
Yes, we all came in the same people. But there will be many people who inhabit Europe now who came from southern Europe and the caucuses. These people came from a later migration from Africa then the cold adapted people who came earlier. There were two migrations out of Africa, and this will determine if a person has called adapted or not.

rzmmm 3y ago

Are you sure it only applies to northern Europeans? The linked article states the genetic variant is found all over the planet, although it's less frequent in Africa.

jyscao 3y ago

>This really only applies to northern Europeans. We are the only cold adapted peoples because of the ice age. Incorrect. Northeast Asians had to deal with arguably harsher cold climates than northern Europeans. Some examples of research on this subject (just the first couple I found through search): * Extreme climate, rather than population history, explains mid-facial morphology of Northern Asians (https://pubmed.ncbi.nlm.nih.gov/24374801/ https://pubmed.ncbi.nlm.nih.gov/24374801/) * Searching for Signatures of Cold Climate Adaptation in TRPM8 Gene in Populations of East Asian Ancestry (https://www.frontiersin.org/articles/10.3389/fgene.2019.00759/full https://www.frontiersin.org/articles/10.3389/fgene.2019.0075...) Not to mention, this article on the zinc metabolism gene variant explicitly states: >Although the variant was established in Asia as a result of interbreeding between Denisovans and sapiens, it also spread to European and native American populations.

Podgajski 3y ago
Those east Asians are carrying the same cold adapted genes from the same people the Northern Europeans got them from. The Denisovans and Neanderthal have a common ancestor. https://evolution.berkeley.edu/wp-content/uploads/2020/08/evo-news-denisovans.jpg https://evolution.berkeley.edu/wp-content/uploads/2020/08/ev... The ice age you’re talking about and what I’m talking about are different. The age I’m talking about is the one that caused that split. And it happened 400,000 years ago. https://cdn.serc.carleton.edu/images/eslabs/cryosphere/timeline_ice_ages_456.webp https://cdn.serc.carleton.edu/images/eslabs/cryosphere/timel... These are extremely ancient cold adaptive genes. From the study: “ Given the essential role of the mitochondria in skeletal muscle thermogenesis, we propose that the derived G allele, which we have shown provides better protection to the mitochondria, may have been positively selected to facilitate adaptation to cold while providing higher susceptibility to neuropsychiatric traits. This is a plausible scenario for a case of archaic adaptive introgression, as Denisovans and Neanderthals were probably already well adapted to the local environmental conditions modern humans encountered when expanding across Eurasia.” I admit to my over generalization Only because it can get too complicated explaining it all on HN.

bitxbitxbitcoin 3y ago

The Western centric view of world history strikes again. The article is talking about Denisovans and last I checked, Denisova Cave wasn’t in Northern Europe.

Podgajski 3y ago
Yeah, I’m sorry I was over generalizing and I was being Eurocentric for a reason. But the Denisovans and the Neanderthals both came from the same ancestor during the Ice Age I’m talking about which was 400,000 years ago. These people were split because of the ice age. And that’s what caused the same cold adapted genes. From the study: Given the essential role of the mitochondria in skeletal muscle thermogenesis, we propose that the derived G allele, which we have shown provides better protection to the mitochondria, may have been positively selected to facilitate adaptation to cold while providing higher susceptibility to neuropsychiatric traits. This is a plausible scenario for a case of archaic adaptive introgression, as Denisovans and Neanderthals were probably already well adapted to the local environmental conditions modern humans encountered when expanding across Eurasia.