2 ms·
I am not exactly an expert, I just happened to do a deep dive into microscopy techniques a couple years ago :-) The general term for these types of techniques
by foota 3y ago
I am not exactly an expert, I just happened to do a deep dive into microscopy techniques a couple years ago :-)
The general term for these types of techniques (e.g., ones that let you image things below the "diffraction limit", which is roughly half the wavelength of light being used to image, see [1]), is super resolution microscopy[2]. There are a few other types you might find interesting.
1: https://en.wikipedia.org/wiki/Diffraction-limited_system https://en.wikipedia.org/wiki/Diffraction-limited_system
2: https://en.wikipedia.org/wiki/Super-resolution_microscopy https://en.wikipedia.org/wiki/Super-resolution_microscopy
- panabee 3y agothanks for sharing, will check these out! based on your understanding, do you think it's possible to do live imaging of RNA molecules < 200 nucleotides -- without altering biological processes? super resolution microscopy references DNA imaging but doesn't delve into contamination risk, which is the critical bit. the first link didn't mention DNA/RNA applications at all. do you mind sharing the other types you recommend investigating?