That’s a lot of caffeine - doesn’t really change the study but also makes it hard infer anything about 1 cup a day. It’s like 4-5 decent sized cups of coffee wo

That’s a lot of caffeine - doesn’t really change the study but also makes it hard infer anything about 1 cup a day. It’s like 4-5 decent sized cups of coffee worth. Actually it’s also beyond what the fda recommends. “ For healthy adults, the FDA has cited 400 milligrams a day—that's about four or five cups of coffee—as an amount not generally associated with dangerous, negative effects” But going to a bit of an extreme makes sense for an early study. If they didn’t see anything with the high caffeine intake, then a low intake would be definitely no noticeable effect. With some effect seen at high doses, now further study should be done. “ 20 young healthy non-smokers (age: 26.4 ± 4.0 years; body mass index: 22.7 ± 1.4 kg/m2; and habitual caffeine intake: 474.1 ± 107.5 mg/day) in a 10-day caffeine (150 mg × 3 times/day), a 10-day placebo (3 times/day), and a withdrawal condition (9-day caffeine followed by 1-day placebo)”