Some of this is universal, but much of her story is particular to how US med schools operate: their research faculty tend to be largely soft money in nature, so

Some of this is universal, but much of her story is particular to how US med schools operate: their research faculty tend to be largely soft money in nature, so grant money is even more necessary than in other 'hard money' jobs in non-med school fields. Such a system is destined to fail when geniuses like Kariko pursue risky new territory for which large grants are hard to secure.