Ozempic was also shown to modify BMR even after controlling for the change in body mass. It is doing something else in addition to aversion therapy. Probably se

Ozempic was also shown to modify BMR even after controlling for the change in body mass. It is doing something else in addition to aversion therapy. Probably several somethings else, not all of which we understand or would want. But again the calorie counting is an oversimplication as mentioned in other posts. Elegantly simple, and so attractive. Caloric restriction will always work in the absence of the endocrine issues you mention. And in the absence of other issues we haven't discovered or don't understand yet. The vast majority of hypothyroidism is due to autoimmune related inflammation (Hashimoto's). The normal cause for that is childbirth related immune response. But plenty of other autoimmune diseases are virally triggered, quite possibly even diabetes. Combining that with the way gut biome impacts appetite and processing efficiency, we can't just pretend telling people to eat less and better and exercise will matter no matter how hard we work on education. Ozempic is a bandaid that rich people will use and will slow down discovery of all the multitudes of ways modern life has conspired to cause obesity.