Not an expert at all but I'm preparing to go through assisting someone with CAR-T therapy soon. This is just from what I've seen with their treatments and visit

Not an expert at all but I'm preparing to go through assisting someone with CAR-T therapy soon. This is just from what I've seen with their treatments and visits so far. In the previous chemotherapy it was dosed at regular intervals and they could make adjustments to the speed of the dose, supplemental medication, and maybe dose size(?) but the close supervision was more or less right around infusion followed by 3 weeks without medical care. With the CAR-T we're looking at about a week of 8 hours every day in the clinic, followed by 3 weeks of slightly fewer days each week. In addition the caretakers (family/friends) are to monitor the patient at all other times for signs of cytokine release and the neurological effects. There are steroids used to reduce the impact of both but they need to be applied fast enough. The patient is supposed to be monitored 24/7 for a month, and for patients who live more than a hour from the clinic they have to stay in a hotel and cannot go home. It seems more serious than the initial chemo cycle but it seems to me that part of that is because they inject the modified cells then just watch.