Age is the main factor affecting outcome. The risk of death in the 70+ cohort was quite high before vaccination, but the risk in the 50+ population was also un

Age is the main factor affecting outcome. The risk of death in the 70+ cohort was quite high before vaccination, but the risk in the 50+ population was also unacceptably high. Vaccines basically had the effect of shifting the curve to the right by 15-20 years, i.e. 70 years old vaccinated has the same risk as 50 years old unvaccinated. After age, yeah, genetics, use of ACE inhibitors, coagulopathy, etc., account for a lot of the remaining risk of death.