You can quite literally inject this RNA product into your arm and nothing would happen. The sequence needs to be specific to a human mRNA in order for silencing

You can quite literally inject this RNA product into your arm and nothing would happen. The sequence needs to be specific to a human mRNA in order for silencing to occur. On top of that you have to deliver the RNA into the cell itself intact. The fact this works is this beetle happens to be responsive to environmental RNA, meaning they could simply take a piece of potato and dip it in beetle specific double stranded RNA, and the larvae would eat it as the delivery mechanism. There is probably some fitness advantage to being able to engage in such uptake normally, and this is what is being taken advantage of here for insecticide purposes.