My initial response was to: "If you are IO-bound, why spend $3000 more on a CPU...", the desktop ones just dont have the PCIe lanes to prevent the I/O bound cas

My initial response was to: "If you are IO-bound, why spend $3000 more on a CPU...", the desktop ones just dont have the PCIe lanes to prevent the I/O bound case. You can run 3 monitors off a iGPU (if you dont care about 3D), overall your setup is a classic desktop, running lots of VM just requires memory as the processes don't do much but exist peacefully. 128GB on a desktop CPU is totally fine with 4 DIMM slots, there won't be ECC - which DDR5 doesn't fully cover, though.