The author was clear what he was setting out to demonstrate in the piece This format is likely very useful for anyone working on such large sets using Jupyter/

The author was clear what he was setting out to demonstrate in the piece This format is likely very useful for anyone working on such large sets using Jupyter/Python and waiting days for scripts to complete -- there is nothing wrong with those final tricky optimisations when applied to single-use scripts I found it a useful reminder that there is often more to be squeezed out on inner loops with a few mins more thought