100 khz is still very fast, with sub-millisecond I2C tranfers possible. You'll have the same issue on any SBC running Linux. You'd need to carefully use realti

100 khz is still very fast, with sub-millisecond I2C tranfers possible. You'll have the same issue on any SBC running Linux. You'd need to carefully use realtime process scheduling, if you want more predictable timing on a general purpose OS for such stringent timing requirements.