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That's not possible with 23andMe data, they have 640,000 SNPs, not the entire genome/exome/methylome. They have 640k points where the genome is often different
by a_bonobo 3y ago
That's not possible with 23andMe data, they have 640,000 SNPs, not the entire genome/exome/methylome. They have 640k points where the genome is often different from others, but your own genome is 3Gbp long (3,000,000,000 basepairs) with usually a few million SNPs per person. 23andMe has a subset of the diversity in your genome.
- upwardbound 3y agoThat's good to know. In that case, my concern would lie with the physical saliva samples that 23andMe has retained, since they could be comprehensively sequenced later.
- a_bonobo 3y agoThat is true! Samples are usually good forever in the freezer. Do they keep all samples? Running -80C freezers is not cheap! I have 3 -80C freezers in my lab, those large chest-freezers, and each uses 22 kWh per day for a total of 66 kWh per day. Apparently the average US household consumes 29 kWh per day, so we use up 2 houses per day. Our freezers certainly don't hold the 14 million samples 23andMe supposedly has, more like in the low thousands. They'd need the power-usage of a city to keep all those samples OK!
- aden1ne 3y agoYou can extract the DNA and store that instead - and they already had to that to their analysis in the first place. Far smaller volume than the raw sample. Storing this for an effectively indefinite amount is not uncommon. I used to work at a clinical genetics lab, and some material had to be stored (by law!) for a whopping 120 years.