4 ms·
> You could sum up Alzheimer's as: Diet/Lifestyle + a congenital form of Cushing's syndrome and you have increasing glucocorticoids which imply downregulation o
by gumby 3y ago
> You could sum up Alzheimer's as: Diet/Lifestyle + a congenital form of Cushing's syndrome and you have increasing glucocorticoids which imply downregulation of the PVN,
Wit all else patients on GLP-1 agonists I wonder if the incidence of Alzheimer’s will decline? I wonder if Semaglutide reduces CRP? There are some preliminary indications that it may: https://cardiab.biomedcentral.com/articles/10.1186/s12933-022-01585-7 https://cardiab.biomedcentral.com/articles/10.1186/s12933-02...
- toomuchtodo 3y agoBetween weight loss, inhibiting addictive behavior, lowering the risk of major cardiovascular events such as stroke, heart attack, and potentially derisking for Alzheimer’s, we should be pumping GLP-1 agonists out like a wartime effort. Likely contributor to fixing 70+ years of socioeconomic configuration that gave us Western Disease and the trimmings that come with it. https://www.bloomberg.com/news/features/2023-10-18/glp-1-drug-benefits-like-ozempic-go-beyond-weight-loss https://www.bloomberg.com/news/features/2023-10-18/glp-1-dru...
- gumby 3y agoT will be interesting to see the side effects of chronic use of these compounds. Still too early to know.