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Thanks! > The concept that a source of mechanical energy exists in the cochlea appeared validated when in the late 70s it was discovered that sound is produced
by tommiegannert 3y ago
Thanks!
> The concept that a source of mechanical energy exists in the cochlea appeared validated when in the late 70s it was discovered that sound is produced by the inner ear. [---] Within five years it was discovered that the outer hair cell could be made to elongate and shorten by electrical stimulation. The function of the outer hair cell in hearing is now perceived as that of a cochlear amplifier that refines the sensitivity and frequency selectivity of the mechanical vibrations of the cochlea.
Like high-resolution variable valve timing in ICEs? Amazing things going on in the body.
> Aspirin has long been known to cause a reversible hearing loss and more recently it has been shown to block otoacoustic emissions. The experiments show that aspirin causes both effects by a direct action on the outer hair cell.
Oh, wow. That sounds like useful information.
- achileas 3y agoAspirin's ototoxicity has been known since at least the 60s, luckily it's reversible. When my advisor did animal studies, they used a similar NSAID (if I remember correctly, it's been a long time) to chemically deafen their animals to then install and test cochlear implants.