I'd also recommend PyO3 and Maturin. The amount of help these crates give is mind boggling (automatic type marshaling and even github CI jobs for creating cross

I'd also recommend PyO3 and Maturin. The amount of help these crates give is mind boggling (automatic type marshaling and even github CI jobs for creating cross platform precompiled wheels). I've created a library using this crate (https://github.com/wiktor-k/pysequoia/ https://github.com/wiktor-k/pysequoia/) and most of the time I could just focus on the problem domain instead of technical details of the bindings. There are just a couple of smaller issues (eg. Python to Rust async is not built in) but overall it's really nice.