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It's more about using DNA/RNA nanostructures. Imagine a 3d tetrahedron with toehold overhangs made entirely of one strand of DNA/RNA that unravel to deliver the
by irollboozers 15y ago
It's more about using DNA/RNA nanostructures. Imagine a 3d tetrahedron with toehold overhangs made entirely of one strand of DNA/RNA that unravel to deliver the payload. From what I remember, they are soluble through lipid bilayers, making them very effective for delivery.
Imagine a very small 3d hotpocket that can deliver small siRNA or miRNA. Even better, you can program a signal amplification or another message into the structure itself, e.g. joining other structures to form lock-key mechanisms like legos.