3 ms·
Oh really? cool. It's been a while since I read anything about viroids. They somehow bundle miRNAs?
by minikomi 15y ago
Oh really? cool. It's been a while since I read anything about viroids. They somehow bundle miRNAs?
- irollboozers 15y agoIt's more about using DNA/RNA nanostructures. Imagine a 3d tetrahedron with toehold overhangs made entirely of one strand of DNA/RNA that unravel to deliver the payload. From what I remember, they are soluble through lipid bilayers, making them very effective for delivery. Imagine a very small 3d hotpocket that can deliver small siRNA or miRNA. Even better, you can program a signal amplification or another message into the structure itself, e.g. joining other structures to form lock-key mechanisms like legos.