5 ms·

So this is the 2005 paper that started it all: https://pubmed.ncbi.nlm.nih.gov/16111635/ https://pubmed.ncbi.nlm.nih.gov/16111635/ I often wonder if, as a lay

by anonu 3y ago

So this is the 2005 paper that started it all: https://pubmed.ncbi.nlm.nih.gov/16111635/ https://pubmed.ncbi.nlm.nih.gov/16111635/ I often wonder if, as a lay person, I would be capable of understanding the significance of really technical papers like this if I were to randomly start reading. Probably not without the right foundation.

ramraj07 3y ago
See if you’re able to read the original Yamanaka iPS paper here. https://www.cell.com/cell/fulltext/S0092-8674(06)00976-7 https://www.cell.com/cell/fulltext/S0092-8674(06)00976-7 I read this as an undergrad and had a blast (inside joke lol). I am considering starting a YouTube channel explaining such breakthroughs while going through the original research. If you’re interested I’ll ping you as focus group when I have some!
- Metacelsus 3y ago
  I read that one in undergrad, it's a great paper.
- anuvrat1 3y ago
  2017 lecture by Shinya Yamanaka[0] is really good, much easier to digest too. [0] - https://youtube.com/watch?v=PTkCDDUbsBc https://youtube.com/watch?v=PTkCDDUbsBc
  - deleted 3y ago
    [deleted]
- mnw21cam 3y ago
  FWIW: BLAST: Basic Local Alignment Search Tool https://blast.ncbi.nlm.nih.gov/Blast.cgi https://blast.ncbi.nlm.nih.gov/Blast.cgi
- felipemnoa 3y ago
  I would love to watch your channel!
  - ramraj07 3y ago
    I’ll make sure to invite you then :)
anuvrat1 3y ago
You can get a rough idea with the right use of chatgpt and Wikipedia while reading any paper, you should give it a try anyway.
j7ake 3y ago
Crazy that it has only been cited about 2000 times over 20 years. Surprising given its impact. This is an example where even citations fail to recognise significant papers. The Doudna Charpentier paper, by contrast, has been cited 17k times and publishes only 12 years ago. As a fun exercise, the journal immunity should provide the reviewer comments to see how things have changed in light of 20 years.
ortusdux 3y ago
You might like https://fermatslibrary.com/ https://fermatslibrary.com/

by anonu 3y ago

ramraj07 3y ago

See if you’re able to read the original Yamanaka iPS paper here. https://www.cell.com/cell/fulltext/S0092-8674(06)00976-7 https://www.cell.com/cell/fulltext/S0092-8674(06)00976-7 I read this as an undergrad and had a blast (inside joke lol). I am considering starting a YouTube channel explaining such breakthroughs while going through the original research. If you’re interested I’ll ping you as focus group when I have some!

Metacelsus 3y ago
I read that one in undergrad, it's a great paper.
anuvrat1 3y ago
2017 lecture by Shinya Yamanaka[0] is really good, much easier to digest too. [0] - https://youtube.com/watch?v=PTkCDDUbsBc https://youtube.com/watch?v=PTkCDDUbsBc
- deleted 3y ago
  [deleted]
mnw21cam 3y ago
FWIW: BLAST: Basic Local Alignment Search Tool https://blast.ncbi.nlm.nih.gov/Blast.cgi https://blast.ncbi.nlm.nih.gov/Blast.cgi
felipemnoa 3y ago
I would love to watch your channel!
- ramraj07 3y ago
  I’ll make sure to invite you then :)

anuvrat1 3y ago

You can get a rough idea with the right use of chatgpt and Wikipedia while reading any paper, you should give it a try anyway.

j7ake 3y ago

Crazy that it has only been cited about 2000 times over 20 years. Surprising given its impact. This is an example where even citations fail to recognise significant papers. The Doudna Charpentier paper, by contrast, has been cited 17k times and publishes only 12 years ago. As a fun exercise, the journal immunity should provide the reviewer comments to see how things have changed in light of 20 years.

ortusdux 3y ago

You might like https://fermatslibrary.com/ https://fermatslibrary.com/