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Is this the first practical, mass deployable remote code execution in a human? Or was there something earlier? I particularly enjoyed the unreasonably effectiv

Is this the first practical, mass deployable remote code execution in a human? Or was there something earlier? I particularly enjoyed the unreasonably effective antivirus bypass achieved by slight modification of the payload by introducing pseudouridine (Ψ), which the antivirus had never seen before and therefore ignored. Such a bypass definitely deserves a Nobel Prize!

xorcist 3y ago
The computer term "virus" was chosen because it has similarities with a virus. Not the other way around...
- slim 3y ago
  similarity is bijective
happytiger 3y ago
It’s kind of exactly what it is tho
- ceejayoz 3y ago
  RCE, yes. The first ever, no.
aredox 3y ago
All viruses are "remote code execution" - including vaccines made from weakened viruses or repurposed viral vectors. mRNA tech is just cutting out a lot of cruft and mass-producing and delivering tiny mRNA strands directly.
- gniv 3y ago
  I don't think weakened viruses go through our protein-making machinery (aka code execution), but directly cause immune system reactions. Edit: I stand corrected.
  - jeltz 3y ago
    Viral vectors on the other hand are.
  - ralusek 3y ago
    Attenuated/weakened viruses still infect cells and go through normal protein-making machinery. Inactivated viruses and subunit/recombinant vaccines, however, just directly expose our immune system to the antigen(s) of the pathogen. mRNA/viral vector/attenuated all involve some degree of "code execution."
  - sampo 3y ago
    > I don't think weakened viruses go through our protein-making machinery (aka code execution) Yes they do. They are live viruses, and they attack cells and hijack their protein-making machinery for making more viruses. But the attenuated vaccine viruses are not capable of causing a severe disease, so in time the body's immune system cleans them out. https://en.wikipedia.org/wiki/Attenuated_vaccine https://en.wikipedia.org/wiki/Attenuated_vaccine
deleted 3y ago
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Beijinger 3y ago
Kind of. Yes. The real question is now: When will it be used in doping? Honestly, I suspect it might be already.

xorcist 3y ago

The computer term "virus" was chosen because it has similarities with a virus. Not the other way around...

slim 3y ago
similarity is bijective

happytiger 3y ago

It’s kind of exactly what it is tho

ceejayoz 3y ago
RCE, yes. The first ever, no.

aredox 3y ago

All viruses are "remote code execution" - including vaccines made from weakened viruses or repurposed viral vectors. mRNA tech is just cutting out a lot of cruft and mass-producing and delivering tiny mRNA strands directly.

gniv 3y ago
I don't think weakened viruses go through our protein-making machinery (aka code execution), but directly cause immune system reactions. Edit: I stand corrected.
- jeltz 3y ago
  Viral vectors on the other hand are.
- ralusek 3y ago
  Attenuated/weakened viruses still infect cells and go through normal protein-making machinery. Inactivated viruses and subunit/recombinant vaccines, however, just directly expose our immune system to the antigen(s) of the pathogen. mRNA/viral vector/attenuated all involve some degree of "code execution."
- sampo 3y ago
  > I don't think weakened viruses go through our protein-making machinery (aka code execution) Yes they do. They are live viruses, and they attack cells and hijack their protein-making machinery for making more viruses. But the attenuated vaccine viruses are not capable of causing a severe disease, so in time the body's immune system cleans them out. https://en.wikipedia.org/wiki/Attenuated_vaccine https://en.wikipedia.org/wiki/Attenuated_vaccine

deleted 3y ago

[deleted]

Beijinger 3y ago

Kind of. Yes. The real question is now: When will it be used in doping? Honestly, I suspect it might be already.