3 ms·

Right, people who have lived natively there have evolved physical coping mechanisms which must be taken into account when they move to other geographical areas.

by car 3y ago

Right, people who have lived natively there have evolved physical coping mechanisms which must be taken into account when they move to other geographical areas. The reverse for "plains" people who move to high altitudes. What coping mechanisms would that be? Right from the beginning i had felt that the whole Sun Exposure/Skin Cancer/Sunscreen debate was nonsensical without understanding the "original adaptations" of the people involved. What "original adaptations" are you referring to? I remember an article which i read a long time ago that posited that all of our modern health/medical dosage "standards" (eg. BMI) are suspect because they were derived from a sample of European Males and hence are not universally applicable across the world. Given what we know today about genetics/epigenetics/adaptation i have always felt that this should be the first thing doctors should consider when treating patients. How about you give us a reference to this article before paraphrasing from memory?

rramadass 3y ago
> What coping mechanisms would that be? One example; King of the Mountains: Tibetan and Sherpa Physiological Adaptations for Life at High Altitude - https://journals.physiology.org/doi/full/10.1152/physiol.00018.2014 https://journals.physiology.org/doi/full/10.1152/physiol.000... > What "original adaptations" are you referring to? That should have been obvious from the context. A people's "native and niche" geographical area in which they evolved to adapt. Eg. Chukchi in the Arctic (tolerance to extreme cold by increased basal metabolic rate and blood pressure), Bajau Freedivers of Indonesia (much larger spleen) etc. More prosaically darker skin as you get closer to the equator and lighter skin as you go away from it. > How about you give us a reference to this article before paraphrasing from memory? How about you understand what is meant when i have said "which i read a long time ago"? I myself have been searching for this for a while now but i don't recall the title and hence am unable to find it. However, One very good example of BMI vs. Fat is this video about the epidemic of diabetes in poor countries that aren't overweight where the British and Indian scientists measure their fat content (the wai wai paradox at 7:40) - https://www.youtube.com/watch?v=aGuED1JczbI https://www.youtube.com/watch?v=aGuED1JczbI

by car 3y ago

rramadass 3y ago

> What coping mechanisms would that be? One example; King of the Mountains: Tibetan and Sherpa Physiological Adaptations for Life at High Altitude - https://journals.physiology.org/doi/full/10.1152/physiol.00018.2014 https://journals.physiology.org/doi/full/10.1152/physiol.000... > What "original adaptations" are you referring to? That should have been obvious from the context. A people's "native and niche" geographical area in which they evolved to adapt. Eg. Chukchi in the Arctic (tolerance to extreme cold by increased basal metabolic rate and blood pressure), Bajau Freedivers of Indonesia (much larger spleen) etc. More prosaically darker skin as you get closer to the equator and lighter skin as you go away from it. > How about you give us a reference to this article before paraphrasing from memory? How about you understand what is meant when i have said "which i read a long time ago"? I myself have been searching for this for a while now but i don't recall the title and hence am unable to find it. However, One very good example of BMI vs. Fat is this video about the epidemic of diabetes in poor countries that aren't overweight where the British and Indian scientists measure their fat content (the wai wai paradox at 7:40) - https://www.youtube.com/watch?v=aGuED1JczbI https://www.youtube.com/watch?v=aGuED1JczbI