First of all - make sure you've covered the quick wins: use nginx, php-fpm, cache as much as possible in memory (PHP's APC is easy enough to use). Make sure tha

First of all - make sure you've covered the quick wins: use nginx, php-fpm, cache as much as possible in memory (PHP's APC is easy enough to use). Make sure that MySQL is optimized and has the same easy quick wins covered (e.g. query cache). And then have fun with the advanced topics :)