You sould branch at the level where inlining doesn't make sense, which would usually be some function wrapping the big loop, which should be rather free. Which

You sould branch at the level where inlining doesn't make sense, which would usually be some function wrapping the big loop, which should be rather free. Which is the same situation as on x86-64 if you want to target pre-AVX2/post-AVX2/AVX-512.