It depends on how fast things are clocked on your board. For anything less than 100MHz, you wouldn't have to think about it. For faster clocks, you might have t

It depends on how fast things are clocked on your board. For anything less than 100MHz, you wouldn't have to think about it. For faster clocks, you might have to be a little wary (but it should be fairly easy for such a low power device with proper ground and power planes, bypassing etc.)