My friend eventually figured out for herself that she has the genetic condition of not being able to methylate the provitamin folic acid into Vitamin B9 (import

My friend eventually figured out for herself that she has the genetic condition of not being able to methylate the provitamin folic acid into Vitamin B9 (important for dna synthesis). She told me how adding L-methylfolate to her routine was like flipping a switch from ‘depressed’ to ‘not-depressed’. #MTHFR: https://twitter.com/jamesknochel/status/1595562181692907520?s=46&t=ycWykCoedyXdwmzwaocL9w https://twitter.com/jamesknochel/status/1595562181692907520?... MAOIs are reasonably effective at lifting people’s moods, and start to work right away - helpful for breaking 'depressions' negative feedback loop. SSRIs were promoted because they were profitable, not because they’re especially effective. Now that the patents have expired the harms of these drugs are getting more attention.