3 ms·

Great except for the ethanol thing...

c7DJTLrn 3y ago
No I haven't been drinking boss... it's the bacteria in my mouth!
matthewtse 3y ago
> It is possible to genetically engineer Streptococcus mutans, the dominant human mouth bacteria, to produce ethanol instead of cavity-causing lactic acid I hope it's in such small quantities that it wouldn't cause any alcoholic effects? Nonetheless, such a simple website with short and concise copy. Wasn't expecting that for a biotech startup. Hope it works, cavities suck!
- ceejayoz 3y ago
  Auto-brewery syndrome! https://www.cbc.ca/radio/quirks/oct-26-2019-world-s-loudest-bird-a-six-fingered-lemur-a-microbrewery-in-your-gut-and-more-1.5334176/beer-belly-a-rare-yeast-infection-makes-the-gut-into-a-microbrewery-1.5334188 https://www.cbc.ca/radio/quirks/oct-26-2019-world-s-loudest-...
  - ILMostro7 3y ago
    This is hilarious. "a walking brewerey". https://i0.wp.com/thebeerthrillers.com/wp-content/uploads/2023/07/Pregnant-Bender.webp?resize=660,509 https://i0.wp.com/thebeerthrillers.com/wp-content/uploads/20... Plus, the first sentence. >Michelle Giannotto knew something was wrong with her husband Donato after he had an infection following a simple nose surgery. The guy's name is Donato Giannotto. Not being mean, just fun to say. Edit: not at all funny and irrelevant, apparently.
isitmadeofglass 3y ago
Probably not going to generate more ethanol than you already get in your morning cup of orange juice
apsec112 3y ago
The amounts produced are tiny. See the safety FAQ here: https://docs.google.com/document/d/1mDJCTO2QySmQOZQcajYReDCA1MFpKs-EZ5E0VNu50Fo/edit?usp=drivesdk https://docs.google.com/document/d/1mDJCTO2QySmQOZQcajYReDCA...
- fauigerzigerk 3y ago
  The quantities are too small to make you drunk, but does it increase your risk of mouth cancer to have this in your mouth all day every day?
  - eqvinox 3y ago
    Better question: do any increased risks from this outweigh the risks incurred from poorer dental health and procedures to address these? (particularly at high age)?
lvh 3y ago
It's pretty unlikely to cause an intoxicating effect: it's surrounded by the mouth, so it'll be taken up almost instantly. It never gets to accumulate, so I'd expect the impact is far less than even something like kombucha. I wonder what the religious implications might be.
- thsksbd 3y ago
  Unless the bacteria makes it past the stomach and inoculates the intestines. Then you get nice and drunk every time you have cake.
gostsamo 3y ago
Yeah, sure. A milliliter of etanol a month versus pain and drop of quality of life. Who would choose that!
gweinberg 3y ago
I'd be willing to give it a shot.
- AnimalMuppet 3y ago
  Pun intended? If so, nicely done!
fbdab103 3y ago
>The average human digestive system produces approximately 3 g of ethanol per day through fermentation of its contents. https://en.wikipedia.org/wiki/Ethanol_metabolism https://en.wikipedia.org/wiki/Ethanol_metabolism

No I haven't been drinking boss... it's the bacteria in my mouth!

> It is possible to genetically engineer Streptococcus mutans, the dominant human mouth bacteria, to produce ethanol instead of cavity-causing lactic acid I hope it's in such small quantities that it wouldn't cause any alcoholic effects? Nonetheless, such a simple website with short and concise copy. Wasn't expecting that for a biotech startup. Hope it works, cavities suck!

ceejayoz 3y ago
Auto-brewery syndrome! https://www.cbc.ca/radio/quirks/oct-26-2019-world-s-loudest-bird-a-six-fingered-lemur-a-microbrewery-in-your-gut-and-more-1.5334176/beer-belly-a-rare-yeast-infection-makes-the-gut-into-a-microbrewery-1.5334188 https://www.cbc.ca/radio/quirks/oct-26-2019-world-s-loudest-...
- ILMostro7 3y ago
  This is hilarious. "a walking brewerey". https://i0.wp.com/thebeerthrillers.com/wp-content/uploads/2023/07/Pregnant-Bender.webp?resize=660,509 https://i0.wp.com/thebeerthrillers.com/wp-content/uploads/20... Plus, the first sentence. >Michelle Giannotto knew something was wrong with her husband Donato after he had an infection following a simple nose surgery. The guy's name is Donato Giannotto. Not being mean, just fun to say. Edit: not at all funny and irrelevant, apparently.

isitmadeofglass 3y ago

Probably not going to generate more ethanol than you already get in your morning cup of orange juice

apsec112 3y ago

The amounts produced are tiny. See the safety FAQ here: https://docs.google.com/document/d/1mDJCTO2QySmQOZQcajYReDCA1MFpKs-EZ5E0VNu50Fo/edit?usp=drivesdk https://docs.google.com/document/d/1mDJCTO2QySmQOZQcajYReDCA...

fauigerzigerk 3y ago
The quantities are too small to make you drunk, but does it increase your risk of mouth cancer to have this in your mouth all day every day?
- eqvinox 3y ago
  Better question: do any increased risks from this outweigh the risks incurred from poorer dental health and procedures to address these? (particularly at high age)?

lvh 3y ago

It's pretty unlikely to cause an intoxicating effect: it's surrounded by the mouth, so it'll be taken up almost instantly. It never gets to accumulate, so I'd expect the impact is far less than even something like kombucha. I wonder what the religious implications might be.

thsksbd 3y ago
Unless the bacteria makes it past the stomach and inoculates the intestines. Then you get nice and drunk every time you have cake.

gostsamo 3y ago

Yeah, sure. A milliliter of etanol a month versus pain and drop of quality of life. Who would choose that!

gweinberg 3y ago

I'd be willing to give it a shot.

AnimalMuppet 3y ago
Pun intended? If so, nicely done!

fbdab103 3y ago

>The average human digestive system produces approximately 3 g of ethanol per day through fermentation of its contents. https://en.wikipedia.org/wiki/Ethanol_metabolism https://en.wikipedia.org/wiki/Ethanol_metabolism