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Scientists improve anti-tumor power of CAR-T cells
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- Ralfp 3y agoI dream of future where cancer of every kind is a fully treatable malady at best, or manageable chronic condition at worst. We are not there yet, but I have a hope that we are no further than century away from achieving that.
- timbit42 3y agoIf we can avoid destroying ourselves, we will achieve it.
- heyoni 3y agoMaybe the notion that we can live for an extended period of time will motivate more people to become ecologically responsible.
- askonomm 3y agoOur hearts would eventually give out anyway. I'd just much rather die of a sudden heart attack than a long and torturous cancer battle.
- JoshTriplett 3y ago> Our hearts would eventually give out anyway. We need to fix that too.
- eternal_braid 3y agoAt some point, it is good to die, to make room for the next generation, no matter how great you are. Others deserve a shot, too.
- JoshTriplett 3y agoNo. Nothing is worth the utter destruction of a person. People have an endless capacity to learn and grow, and there is no limited room for people that's getting used up; the universe is a very big place. Longevity will certainly lead to some interesting challenges; bring them on, they're worth solving and none of them are worth killing people to avoid. And preventing people from living is absolutely equivalent to killing them.
- raffraffraff 3y agoPersonally, for me I'd say "no". But I decided not to have kids, and I don't think you can have unlimited reproduction and immortality. It would be interesting to give people the choice between eternal life and kids. Like in the Highlander, your "prize" for having kids is mortality.
- DoreenMichele 3y agoI wish.
- gretyuph 3y ago[dead]
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- cyberax 3y agoThey used DCA (dichloroacetate) to do the inhibition. It's going to be ironic, if DCA will actually be useful for cancer treatment. For those who don't know, DCA treatment made a lot of noise in the early 2000-s, with all kinds of conspiracy theories about it. Like drug companies covering it up because it "can't be patented". People even crowd-funded its clinical trials. Unfortunately, it turned out to be too toxic on its own because cancer cells can adapt to the levels of DCA that kill the rest of the patient.
- askonomm 3y agoI'm 31 which means I got maybe around 20? years before I become a prime target of potential cancers. I really hope by then most of even today's abilities are at least available in most hospitals, since right now cancer treatment in Estonia is still old-school chemotherapy. Not even sure if our doctors have heard of Car-T. 20 years is probably too little time to make dying from cancer a thing of the past, but maybe getting today's cutting edge mainstream by then would be possible.
- adamredwoods 3y agoImmunotherapy is the direction we want to go, but Car-T therapy can kill the patient. Old school chemotherapy still works as a first-line defense, and the newer stuff is getting better (paclitaxel, antibody drug conjugates (ADC)).
- puchatek 3y agoLooking at major developments in the world I feel like we're moving away from societies that enable the best healthcare for as many as possible and rather move to nationalistic, authoritarian states that drag everybody back into a 20th century mindset. Money spent on defence won't be spent on research and sure as hell not on affordable healthcare. The tech might be there when you hit 50 but will you be able to afford it?
- askonomm 3y agoYeah, I tend to agree. Next year I'm moving away from Estonia, to Finland, precisely because at least there the government still cares to a point about healthcare whereas here they have entirely given up, defund it on a regular basis, and gatekeep access to specialists via family doctors who don't allow you to go anywhere and instead of any tests give you pills. All sorts of pills. Knee pain? Antidepressants on a Tuesday, ibuprofen on a Wednesday. People don't get help, just suppressing of symptoms (in the best case) and told to go die somewhere (in the worst case). And that would be fine and all, and I wouldn't even care, if I didn't have to pay half my salary to taxes. If I could choose to not pay healthcare tax, I could use that money to get a very, very nice private healthcare insurance instead. But I'm not allowed to choose here.
- DoreenMichele 3y agoStudy after study after study says diet and lifestyle are major factors in every deadly disease. But it's not socially acceptable to suggest that as an approach. However, having already committed the unspeakable sin and egregious faux pas, I will suggest that if cancer is a thing you fret about, you can do something to reduce your risk starting today.
- gropo 3y agoill never eat PFAS again
- DoreenMichele 3y agoGood for you. Want to share any good websites you have for how to support your goal here? If I'm eating PFAS, I'd like to know.
- klipt 3y agoPFAS (aka "forever chemicals") are present in everything including drinking water and breast milk so yes, you are eating PFAS.
- jncfhnb 3y agoDiet and exercise are near-universally accepted as reasonable health advice and is basically ubiquitous.
- DoreenMichele 3y agoI'm aware of that. It doesn't matter. You can't have a meaty discussion about this in relation to actually trying in earnest to avoid or delay cancer. For the record, this was posted as a PSA without replying to any of the comments that made me think people could use a reminder because a direct reply gets interpreted as a personal attack.
- jjtheblunt 3y ago
- adamredwoods 3y agoThere was another news bit recently re: polyethylene glycol, to reduce the damage done to healthy cells. https://penntoday.upenn.edu/news/suit-armor-cancer-fighting-cells https://penntoday.upenn.edu/news/suit-armor-cancer-fighting-...
- tibbydudeza 3y agoWe should mimic the elephant - they have 20 variations of p53 gene in their DNA - bigger body mass and similiar lifespan but more cells but they don't get cancer.