4 ms·
Thanks for this... % Mutated genes with at least 1 allele classified as benign: 95.72% % Mutated genes with at least 1 allele classified as ambiguous: 2.71%
by kugutsumen 3y ago
Thanks for this...
% Mutated genes with at least 1 allele classified as benign: 95.72%
% Mutated genes with at least 1 allele classified as ambiguous: 2.71%
% Mutated genes with at least 1 allele classified as pathogenic: 1.57%
% Mutated genes with 2 alleles classified as benign: 38.37%
% Mutated genes with 2 alleles classified as ambiguous: 0.54%
% Mutated genes with 2 alleles classified as pathogenic: 0.39%
The first one I checked freaked me out a bit (I have the AA mutation):
MTHFR C677T (Rs1801133). This mutation (the A allele) is associated with reduced enzyme activity, elevated total homocysteine levels and altered distribution of folate [1]. People with an “A” allele for this mutation present a 35% decrease of the normal enzyme activity and “AA” individuals a 70% decrease...
- belval 3y agoFrankly once you go down that rabbit hole you have to make sure that you aren't prone to anxiety. I wrote a tool (not sure if open-sourced) that just crosses the output of 23andme with dbSNP and the number of possible diseases that came up was impressive. I did have the SIRT1 mutation associated with a long life so there's that.