I think the problems are enormous. Fixing them requires either many small, incremental changes or some large, sweeping changes like the one you suggest. My pro

I think the problems are enormous. Fixing them requires either many small, incremental changes or some large, sweeping changes like the one you suggest. My proposal is meant to be incremental, beneficial, and implementable, since it can be adopted by individual actors in the scientific ecosystem. It has the obvious imperfection of not solving all or most of the problems. In terms of sweeping changes, I'm in favor but we need to get the answer right. Corporate science generally fails to pursue long-term research aims. Taking an example from the history of electricity, it was more than 200 years from William Gilbert's isolation of static electric attraction until electricity was commercialized. If science is to be owned by business, business will need to think on timeframes many times longer than it currently does. If people were interested, I could produce a proposal for overhauling science in general. One important challenge is the need to think about both (1) scientific progress, and (2) how science fits into society. Approaches to both need to change.