There are many such signals and they are already being exploited by pathogens. Such things are also exploited by tumors. That's why figuring out hard basic immu

There are many such signals and they are already being exploited by pathogens. Such things are also exploited by tumors. That's why figuring out hard basic immunology problems like transplantation (while managing associated infections) will probably generate knowledge that is likely to help cure cancer, and vice versa. A lot of the time glycans (sugars) are a key part of what makes something look like self vs non-self. Regulatory T cells and infection: a dangerous necessity https://www.nature.com/articles/nri2189 https://www.nature.com/articles/nri2189 Sialic acid utilization by bacterial pathogens https://www.microbiologyresearch.org/content/journal/micro/10.1099/mic.0.2007/009480-0#tab2 https://www.microbiologyresearch.org/content/journal/micro/1... Hallmarks of glycosylation in cancer https://www.oncotarget.com/article/8155/text/ https://www.oncotarget.com/article/8155/text/