3 ms·

> Its like common knowledge Why don't you just say folk wisdom? Commonly rumored? Calling something "knowledge" doesn't make it such. The entire point of scien

> Its like common knowledge Why don't you just say folk wisdom? Commonly rumored? Calling something "knowledge" doesn't make it such. The entire point of science, and the reason it's so ridiculously hard, is that common knowledge is so frequently wrong. > I would not take this every day for a month even if you offer me a years salary. Then don't? No one is asking you to, nor is this trial nor the proposed line of treatment anything like this. > Every medic who thinks this is a good idea should do the self test in my opinion. I have a better proposal: how about they do a bunch of solid RCTs on it? That way we get actual information instead of noise.

randomNumber7 3y ago
I'm also I since guy, so I'm not against what you are saying. Your just twisting my words. You know the story of mdma? It was developed for medical use... And I sayd im skeptical of this, because I cannot imagin, that any serious study, considering the risks comes to this conclusion. Unless it literally stops people from suicid. But as far as I know it's more probable to increase this risk so idk.
- ethanbond 3y ago
  But dude, that's the whole point of these studies! It's really hard to know what a given drug does! We should absolutely factor in people's subjective experiences and recreational experiments in terms of deciding whether it's worth investigating something more thoroughly, but once real, high-quality studies are done (especially RCTs), people's recreational experiences hold very little water when they are in conflict with the study.
  - randomNumber7 3y ago
    Yes I also misunderstood the usage. They make a therapy session once a month where the patient gets high before the session. On the other hand, they dont factor in the body mass of the patient and give everyone the same dosage. That doesnt seem high quality to me. And 120-180mg isn't just a little. Thats at the upper end of what you would take when you go to a party, just for reference. Give this to someone with 60kg body mass and they can have a very bad experience.
    - ethanbond 3y ago
      The dosages are discovered and defined by the Phase I trial, also in a very systematic way that is meant to break free of folk wisdom about correct dosages.
randomNumber7 3y ago
> I have a better proposal: how about they do a bunch of solid RCTs on it? Good but somehow a lot of medics give ritalin to kids. If you would buy some ritalin, and also some speed. Try both and realize it is pretty similiar. I know someone in his mid twenties who has a tremor in his left hand because he had to take this since the age of 10. And maybe there are cases where it makes sense. But defenitely not in that amount. Idgaf about what anyone tells me about this.

randomNumber7 3y ago

I'm also I since guy, so I'm not against what you are saying. Your just twisting my words. You know the story of mdma? It was developed for medical use... And I sayd im skeptical of this, because I cannot imagin, that any serious study, considering the risks comes to this conclusion. Unless it literally stops people from suicid. But as far as I know it's more probable to increase this risk so idk.

ethanbond 3y ago
But dude, that's the whole point of these studies! It's really hard to know what a given drug does! We should absolutely factor in people's subjective experiences and recreational experiments in terms of deciding whether it's worth investigating something more thoroughly, but once real, high-quality studies are done (especially RCTs), people's recreational experiences hold very little water when they are in conflict with the study.
- randomNumber7 3y ago
  Yes I also misunderstood the usage. They make a therapy session once a month where the patient gets high before the session. On the other hand, they dont factor in the body mass of the patient and give everyone the same dosage. That doesnt seem high quality to me. And 120-180mg isn't just a little. Thats at the upper end of what you would take when you go to a party, just for reference. Give this to someone with 60kg body mass and they can have a very bad experience.
  - ethanbond 3y ago
    The dosages are discovered and defined by the Phase I trial, also in a very systematic way that is meant to break free of folk wisdom about correct dosages.

randomNumber7 3y ago

> I have a better proposal: how about they do a bunch of solid RCTs on it? Good but somehow a lot of medics give ritalin to kids. If you would buy some ritalin, and also some speed. Try both and realize it is pretty similiar. I know someone in his mid twenties who has a tremor in his left hand because he had to take this since the age of 10. And maybe there are cases where it makes sense. But defenitely not in that amount. Idgaf about what anyone tells me about this.